doxycycline – this is known to interact with alcohol, and the effectiveness of doxycycline may be reduced in people with a history of chronic alcohol consumption; it should not be taken by people with liver problems Usually, drinking alcohol won’t keep your antibiotic from working to treat your infection. Still, it can interfere with your infection’s healing in other ways. Alcohol and Doxycycline. While alcohol is not prohibited while being treated with doxycycline it is also no recommended. While one to two drinks will not cause adverse effects, if you binge drink or are a chronic alcohol drinker the effectiveness of the medication can be lessened. Yes, it will be safe for you to drink alcohol 48 hours after stopping your medication. In fact you can even drink alcohol while you are taking the doxycycline. When determining the safety of using doxycycline and alcohol, there are several factors which must be considered. The first is what any given person considers “safe.” While combining these substances may not cause an instantaneous reaction, alcohol has been shown to reduce the effectiveness of Doxycycline is a class of medications called tetracycline antibiotics and is used to treat bacterial infections such as respiratory infections like pneumonia, malaria, Lyme disease, acne, bacterial skin infections, genital and urinary infections and inhaled anthrax disease. Doxycycline is an antibiotic used to treat a range of bacterial infections. While drinking alcohol while taking certain antibiotics can be risky, it’s generally safe to consume alcohol while. Is combining doxycycline and alcohol safe or isn’t it? The answer to that question, like with many drug interactions, is a bit tricky. Almost every other type of antibiotic comes with a warning against taking alcohol in combination with this antibiotic. Avoid drinking alcohol with doxycycline. Alcohol can stop it working properly. Speak to your doctor or pharmacist if you have questions about this. Alcohol can stop it working properly. Speak to your doctor or pharmacist if you have questions about this. Iron can bind to doxycycline in the gastrointestinal tract, which may prevent their absorption into the bloodstream and possibly reduce their effectiveness.